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Dianova公司為德國的病理免疫組化產品供應商，具備先進的抗體制備工藝及嚴格的質控系統，產品在上享有良好的聲譽。
Dianova DIA-H09-M說明書
Art.-Nr.
DIA-H09
特異性
IDH1 R132H
物種反應性
人的
寄主物種
老鼠
同型
的IgG2a
克隆
H09
克隆性（單克隆/多克隆）
單克隆
應用
免疫組化（石蠟包埋切片）
Western Blot
免疫組化（IHC）
稀釋
組織/細胞化學1:20
格式
純化的凍干抗體（來自培養上清液）
產品系列/主題
腫瘤標志物/生物學
神經生物學
有可能的使用
用于體外診斷用途
溫度 - 儲存
2-8℃
搜索代碼
DIAH09
IHC，FFPE，石蠟
制造商/品牌
dianova
抗IDH1 R132H抗體克隆H09（由dianova授權給德國癌癥研究中心）提供不同的CE IVD標記格式：
目錄號 | 產品 | 形成 | 狀態 | 數量 | 價錢 |
DIA-H09 | 抗IDH1 R132H，克隆H09 | 濃縮，凍干 | CE IVD | 500μl | 482,00€ |
DIA-H09-M | 抗IDH1 R132H，克隆H09 | 濃縮，凍干 | CE IVD | 100μl | 142,00€ |
MAD-000475QD-3 | 抗IDH1 R132H，克隆H12 | 預先稀釋，即用型 | CE IVD | 3毫升 | 264,00€ |
MAD-000475QD-7 | 抗IDH1 R132H，克隆H15 | 預先稀釋，即用型 | CE IVD | 7毫升 | 482,00€ |
MAD-000475QD-12 | 抗IDH1 R132H，克隆H18 | 預先稀釋，即用型 | CE IVD | 12毫升 | 826,00€ |
福爾馬林固定石蠟包埋的腦組織切片中人IDH1 R132H的免疫組織化學
A：IDH1突變特異性抗體克隆H09在間變性少突細胞瘤的腫瘤中心的強烈反應。
B：間變性星形細胞瘤的浸潤區，通過抗體克隆H09特異性標記浸潤性神經膠質瘤細胞。
C：用抗體克隆H09鑒定遠離腫瘤中心的白質中的單個腫瘤細胞。
D：由少突神經膠質瘤浸潤的皮質，具有抗體克隆H09對腫瘤細胞的特異性標記。
E：GFAP（膠質原纖維酸性蛋白，紅色）和少突膠質細胞瘤浸潤區的H09（棕色）的雙重染色，證明腫瘤細胞的特異性標記但不是GFAP陽性反應性星形膠質細胞的特異性標記。
F：抗體克隆H09與IDH1 R132H突變的彌漫性星形細胞瘤（左）的強烈反應，但不與野生型腫瘤（右）反應。
（圖片由德國海德堡大學海德堡大學神經病理學系/
德國癌癥研究中心（DKFZ）臨床合作單位神經病理學系醫學博士Andreas von Deimling提供）
背景
抗體克隆 H09與福爾馬林固定腦腫瘤組織切片中異檸檬酸脫氫酶1 （IDH1）R132H點突變特異性反應。IDH1密碼子132的雜合點突變在世界衛生組織（WHO）II級和III級神經膠質瘤中很常見。IDH1 R132H突變發生在大約70％的星形細胞瘤和少突神經膠質瘤中。IDH1 R132H突變在特定腦腫瘤實體中的高頻率和分布允許通過免疫組織化學對各種腫瘤的高度敏感和特異性區分，例如來自原發性膠質母細胞瘤的間變性星形細胞瘤或來自毛細胞星形細胞瘤或室管膜瘤的彌散性星形細胞瘤WHO II級。值得注意的是，從反應性神經膠質增生中識別具有IDH1突變的腫瘤的浸潤邊緣。
ATRX（dianova clone AX1）和IDH1R132H（dianova clone H09）的組合免疫組織化學
取代了分子檢測。
用于診斷星形細胞瘤和少突神經膠質瘤的常規實用方法開始于針對IDH1 R132H和ATRX表達的進行IHC 。用ATRX和IDH1 R132H的初始IHC逐步分析分子參數，然后進行1p / 19q分析，然后通過IDH測序，顯著減少了明確診斷所需的分子檢測次數（Reuss等，2015）。
比較研究
參考
SKU | Product Name | Quantity | Price |
DIA-H09 | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09) | 500 µl | 482,00 € plus VAT
Free shipping inside Germany |
DIA-H09-L | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09) - prediluted RTU | 8 ml | 482,00 € plus VAT
Free shipping inside Germany |
DIA-H09-M | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09) | 0,1 ml | 142,00 € plus VAT |
Dianova2019年產品價格表
貨號 | 品名 | 規格 | 價格 | 品牌 |
DIA-100 | Anti-Fibroblasten (CD90) (Hu) from Mouse (Clone: AS02) | 200µg | 4680 | dianova |
DIA-100-M | Anti-Fibroblasten (CD90) (Hu) from Mouse (Clone: AS02) | 20µg | 0 | dianova |
DIA-120 | Anti-Fibroblasten (CD90) (Hu) from Mouse (Clone: AS02) -FITC | 100test | 5360 | dianova |
DIA-530-P05 | Anti-p53 (Hu) from Mouse (Clone: CC53) | 0.5ml | 4780 | dianova |
DIA-530-M | Anti-p53 (Hu) from Mouse (Clone: CC53) | 0.1ml | 0 | dianova |
DIA-670-P05 | Anti-Ki-67/MIB1 (Hu) from Mouse (Clone: Ki-67P) CE-IVD | 0.5ml | 4780 | dianova |
DIA-670-P1 | Anti-Ki-67/MIB1 (Hu) from Mouse (Clone: Ki-67P) CE-IVD | 1ml | 6500 | dianova |
DIA-670-M | Anti-Ki-67/MIB1 (Hu) from Mouse (Clone: Ki-67P) CE-IVD | 0.1ml | 0 | dianova |
DIA-700-P05 | Anti-GFAP (Hu) from Mouse (Clone: IF3) CE-IVD | 0.5ml | 4780 | dianova |
DIA-700-M | Anti-GFAP (Hu) from Mouse (Clone: IF3) CE-IVD | 0.5ml | 0 | dianova |
DIA-AX1 | Anti-ATRX (Hu) from Mouse (Clone: AX1) | 0.5ml | 6760 | dianova |
DIA-CAL-100 | Anti-CALRETICULIN mutation (Hu) from Mouse (Clone CAL2) | 0.1ml | 5960 | dianova |
DIA-CAL-250 | Anti-CALRETICULIN mutation (Hu) from Mouse (Clone CAL2) | 0.25ml | 13960 | dianova |
DIA-H09 | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09) CE-IVD | 0.5ml | 9640 | dianova |
DIA-H09-M | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09) CE-IVD | 0.1ml | 2840 | dianova |
DIA-H09-L | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09), prediluted, ready-to-use | 8ml | 9640 | dianova |
DIA-W09 | Anti-IDH1 (Hu) from Rat (Clone: W09) | 0.5ml | 4960 | dianova |
DIA-TG1 | Anti-TIGIT (Hu) from Mouse (Clone TG1) | 0.5ml | 20400 | dianova |
DIA-TG1-M | Anti-TIGIT (Hu) from Mouse (Clone TG1) | 0.1ml | 5720 | dianova |
DIA-TC8 | Anti-CD8 (Hu) from Mouse (Clone TC8 ) | 0.5ml | 9200 | dianova |
DIA-P16-OD | Anti-P16 (Hu) from Mouse (Clone JAP16) | 0.1ml | 7360 | dianova |
DIA-303 | Anti-CD3 (Ms, FFPE) from Rat (Clone: HH3E) | 0.5ml | 6900 | dianova |
DIA-310 | Anti-CD31 (Ms, FFPE) from Rat (Clone: SZ31) | 0.5ml | 8040 | dianova |
DIA-404 | Anti-CD4 (Ms, FFPE) from Rat (Clone GHH8) | 0.2ml | 6900 | dianova |
DIA-808 | Anti-CD8a (Ms, FFPE) from Rat (Clone GHH8) | 0.2ml | 6900 | dianova |
DIA-60 | Anti-FasL, soluble (Hu) from Mouse (Clone: 94) | 1ml | 4760 | dianova |
DIA-900-100 | Anti-HIS-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone: 13/45/31) | 100µg | 2960 | dianova |
DIA-900-200 | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone: 13/45/31) | 200µg | 5160 | dianova |
DIA-900-FITC | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone:13/45/31) -FITC | 1ml | 5960 | dianova |
DIA-900-BIOT | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone:13/45/31) -Biotin | 100µg | 3960 | dianova |
DIA-910-200-ABF | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone:13/45/31) Acid/BSA-free | 200µg | 4960 | dianova |
DIA.910-1MG-ABF | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone:13/45/31) Acid/BSA-free | 1mg | 19840 | dianova |
SCR-028841 | IS Adhesion Slides | 50pcs. | 1620 | dianova |
SCR-028855 | IS Adhesion Slides | 5pcs. | 詢價 | dianova |
SCR-028842 | IS Adhesion Slides | 100pcs. | 2440 | dianova |
SCR-038447 | Immunoselect Antifading Mounting Medium | 15ml | 960 | dianova |
SCR-038587 | Immunoselect Antifading Mounting Medium | 1ml | 詢價 | dianova |
SCR-038448 | Immunoselect Antifading Mounting Medium DAPI | 15ml | 1180 | dianova |
SCR-038588 | Immunoselect Antifading Mounting Medium DAPI | 1ml | 詢價 | dianova |
SCR-038449 | Immunoselect Antifading Mounting Medium PI | 15ml | 1180 | dianova |
SCR-072967 | Immunoselect Mounting Medium without hardener | 15ml | 960 | dianova |
SCR-093035 | Immunoselect Antifading Mounting Medium DAPI without hardener | 15ml | 1180 | dianova |
SCR-093036 | Immunoselect Antifading Mounting Medium PI without hardener | 15ml | 1180 | dianova |
DIA-0302-I | p53-auto antibody ELISA-Kit (Human) CE-IVD | 96test | 10960 | dianova |
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